Cargando…
Development of a Novel Series of Anticancer and Antidiabetic: Spirothiazolidines Analogs
4-(4-Aminophenyl)-1-thia-4-azaspiro[4.5]decan-3-one 1 was prepared and allowed to react with nitrogen nucleophiles to give the corresponding hydrazones 2–4. Further, compound 1 underwent diazotization and afforded the parallel hydrazono derivative 5; moreover, compound 1 refluxed with active methyle...
Autores principales: | Flefel, Eman M., El-Sofany, Walaa I., Al-Harbi, Reem A.K., El-Shahat, Mahmoud |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650905/ https://www.ncbi.nlm.nih.gov/pubmed/31324043 http://dx.doi.org/10.3390/molecules24132511 |
Ejemplares similares
-
Synthesis, Molecular Docking and In Vitro Screening of Some Newly Synthesized Triazolopyridine, Pyridotriazine and Pyridine–Pyrazole Hybrid Derivatives
por: Flefel, Eman M., et al.
Publicado: (2018) -
Synthesis of Some New Pyridazine Derivatives for Anti-HAV Evaluation
por: Flefel, Eman M., et al.
Publicado: (2017) -
Synthesis and Anticancer Activity of New 1-Thia-4-azaspiro[4.5]decane, Their Derived Thiazolopyrimidine and 1,3,4-Thiadiazole Thioglycosides
por: Flefel, Eman M., et al.
Publicado: (2017) -
Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives
por: Nossier, Eman S., et al.
Publicado: (2018) -
Application of Artificial Intelligence in Discovery and Development of Anticancer and Antidiabetic Therapeutic Agents
por: Alqahtani, Amal
Publicado: (2022)