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Classification of Functional Metagenomes Recovered from Different Environmental Samples

Classification of functional metagenomes from the microbial community plays the vital role in the metagenomics research. In this paper, an investigation was made to study the performance of beta-t random forest classifier for classification of metagenomics data. Nine key functional meta-genomic vari...

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Autores principales: Akond, Zobaer, Hasan, Mohammad Nazmol, Alam, Md.Jahangir, Alam, Munirul, Mollah, Md.Nurul Haque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651027/
https://www.ncbi.nlm.nih.gov/pubmed/31359995
http://dx.doi.org/10.6026/97320630015026
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author Akond, Zobaer
Hasan, Mohammad Nazmol
Alam, Md.Jahangir
Alam, Munirul
Mollah, Md.Nurul Haque
author_facet Akond, Zobaer
Hasan, Mohammad Nazmol
Alam, Md.Jahangir
Alam, Munirul
Mollah, Md.Nurul Haque
author_sort Akond, Zobaer
collection PubMed
description Classification of functional metagenomes from the microbial community plays the vital role in the metagenomics research. In this paper, an investigation was made to study the performance of beta-t random forest classifier for classification of metagenomics data. Nine key functional meta-genomic variables were selected using the beta-t test statistic from the 10 different microbial community using p-value at 5% level of significance. Then beta-t random forest classifier showed the higher accuracy (96%), true positive rate (96%) and lower false positive rate (5%), false discovery rate (5%) and misclassification error rate (5%) for classification of metagenomes. This method showed the better performance compare to Bayes, SVM, KNN, AdaBoost and LogitBoost).
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spelling pubmed-66510272019-07-29 Classification of Functional Metagenomes Recovered from Different Environmental Samples Akond, Zobaer Hasan, Mohammad Nazmol Alam, Md.Jahangir Alam, Munirul Mollah, Md.Nurul Haque Bioinformation Research Article Classification of functional metagenomes from the microbial community plays the vital role in the metagenomics research. In this paper, an investigation was made to study the performance of beta-t random forest classifier for classification of metagenomics data. Nine key functional meta-genomic variables were selected using the beta-t test statistic from the 10 different microbial community using p-value at 5% level of significance. Then beta-t random forest classifier showed the higher accuracy (96%), true positive rate (96%) and lower false positive rate (5%), false discovery rate (5%) and misclassification error rate (5%) for classification of metagenomes. This method showed the better performance compare to Bayes, SVM, KNN, AdaBoost and LogitBoost). Biomedical Informatics 2019-01-31 /pmc/articles/PMC6651027/ /pubmed/31359995 http://dx.doi.org/10.6026/97320630015026 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Akond, Zobaer
Hasan, Mohammad Nazmol
Alam, Md.Jahangir
Alam, Munirul
Mollah, Md.Nurul Haque
Classification of Functional Metagenomes Recovered from Different Environmental Samples
title Classification of Functional Metagenomes Recovered from Different Environmental Samples
title_full Classification of Functional Metagenomes Recovered from Different Environmental Samples
title_fullStr Classification of Functional Metagenomes Recovered from Different Environmental Samples
title_full_unstemmed Classification of Functional Metagenomes Recovered from Different Environmental Samples
title_short Classification of Functional Metagenomes Recovered from Different Environmental Samples
title_sort classification of functional metagenomes recovered from different environmental samples
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651027/
https://www.ncbi.nlm.nih.gov/pubmed/31359995
http://dx.doi.org/10.6026/97320630015026
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