Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM)

Bovine respiratory disease (BRD) and bovine mastitis (BM) are the most common and costly infectious diseases in beef cattle and dairy cattle, respectively. In the current study, we evaluated the antimicrobial activity of seven phytochemicals against twelve BRD- and/or BMcausing bacterial pathogens....

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Autores principales: Rajamanickam, Karthic, Yang, Jian, Sakharkar, Meena Kishore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651029/
https://www.ncbi.nlm.nih.gov/pubmed/31359996
http://dx.doi.org/10.6026/97320630015032
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author Rajamanickam, Karthic
Yang, Jian
Sakharkar, Meena Kishore
author_facet Rajamanickam, Karthic
Yang, Jian
Sakharkar, Meena Kishore
author_sort Rajamanickam, Karthic
collection PubMed
description Bovine respiratory disease (BRD) and bovine mastitis (BM) are the most common and costly infectious diseases in beef cattle and dairy cattle, respectively. In the current study, we evaluated the antimicrobial activity of seven phytochemicals against twelve BRD- and/or BMcausing bacterial pathogens. Our results show that allyl isothiocyanate, benzyl isothiocynate, cinnamaldehyde and eugenol are effective against most of the BRD- and/or BM-causing bacterial pathogens and could be repurposed as alternatives to antibiotics for the prevention/elimination of BRD and BM in feedlots.
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spelling pubmed-66510292019-07-29 Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM) Rajamanickam, Karthic Yang, Jian Sakharkar, Meena Kishore Bioinformation Research Article Bovine respiratory disease (BRD) and bovine mastitis (BM) are the most common and costly infectious diseases in beef cattle and dairy cattle, respectively. In the current study, we evaluated the antimicrobial activity of seven phytochemicals against twelve BRD- and/or BMcausing bacterial pathogens. Our results show that allyl isothiocyanate, benzyl isothiocynate, cinnamaldehyde and eugenol are effective against most of the BRD- and/or BM-causing bacterial pathogens and could be repurposed as alternatives to antibiotics for the prevention/elimination of BRD and BM in feedlots. Biomedical Informatics 2019-02-03 /pmc/articles/PMC6651029/ /pubmed/31359996 http://dx.doi.org/10.6026/97320630015032 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Rajamanickam, Karthic
Yang, Jian
Sakharkar, Meena Kishore
Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM)
title Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM)
title_full Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM)
title_fullStr Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM)
title_full_unstemmed Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM)
title_short Phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(BRD)and bovine mastitis(BM)
title_sort phytochemicals as alternatives to antibiotics against major pathogens involved in bovine respiratory disease(brd)and bovine mastitis(bm)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651029/
https://www.ncbi.nlm.nih.gov/pubmed/31359996
http://dx.doi.org/10.6026/97320630015032
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