Cargando…
Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation
Licochalcone A, a flavonoid extracted from licorice root, has been shown to exhibit broad anti-inflammatory, anti-bacterial, anticancer, and antioxidative bioactivity. In this study, we investigated the antitumor activity of Licochalcone A against human osteosarcoma cell lines. The data showed that...
Autores principales: | Shen, Tai-Shan, Hsu, Yung-Ken, Huang, Yi-Fu, Chen, Hsuan-Ying, Hsieh, Cheng-Pu, Chen, Chiu-Liang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651087/ https://www.ncbi.nlm.nih.gov/pubmed/31269698 http://dx.doi.org/10.3390/molecules24132435 |
Ejemplares similares
-
Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells
por: Tsai, Jen-Pi, et al.
Publicado: (2015) -
Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy
por: Manic, Gwenola, et al.
Publicado: (2015) -
An ATM–Chk2–INCENP pathway activates the abscission checkpoint
por: Petsalaki, Eleni, et al.
Publicado: (2020) -
7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells
por: Chang, Mei-Chi, et al.
Publicado: (2016) -
Licochalcone A Suppresses Renal Cancer Cell Proliferation and Metastasis by Engagement of Sp1-Mediated LC3 Expression
por: Tseng, Tsai-Yi, et al.
Publicado: (2023)