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Maternal and Post-Weaning High-Fat Diets Produce Distinct DNA Methylation Patterns in Hepatic Metabolic Pathways within Specific Genomic Contexts

Calorie-dense high-fat diets (HF) are associated with detrimental health outcomes, including obesity, cardiovascular disease, and diabetes. Both pre- and post-natal HF diets have been hypothesized to negatively impact long-term metabolic health via epigenetic mechanisms. To understand how the timing...

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Detalles Bibliográficos
Autores principales: Moody, Laura, Wang, Huan, Jung, Paul M., Chen, Hong, Pan, Yuan-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651091/
https://www.ncbi.nlm.nih.gov/pubmed/31262088
http://dx.doi.org/10.3390/ijms20133229