Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma

R428, a selective small molecule Axl inhibitor, is known to have anti-cancer effects, such as inhibition of invasion and proliferation and induction of cell death in cancer cells. The Axl receptor tyrosine kinase is highly expressed in cancer cells and the level of Axl expression is associated with...

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Detalles Bibliográficos
Autores principales: Woo, Seon Min, Min, Kyoung-jin, Seo, Seung Un, Kim, Shin, Kubatka, Peter, Park, Jong-Wook, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651098/
https://www.ncbi.nlm.nih.gov/pubmed/31269715
http://dx.doi.org/10.3390/ijms20133253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651098/
https://www.ncbi.nlm.nih.gov/pubmed/31269715
http://dx.doi.org/10.3390/ijms20133253

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