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Antitussive and Anti-inflammatory Dual-active Agents Developed from Natural Product Lead Compound 1-Methylhydantoin

Natural products play an important role in drug discovery. This work employed a natural product 1-methylhydantoin as the lead compound to develop novel dual-active drugs. 1-Methylhydantoin was isolated from Oviductus Ranae, which is a traditional Chinese medicine that has been used for tussive and i...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Wang, Fang, Guo, Hongye, Wang, Shihan, Ni, Shuling, Zhou, Yan, Wang, Zhihan, Bao, Huiwei, Wang, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651114/
https://www.ncbi.nlm.nih.gov/pubmed/31247960
http://dx.doi.org/10.3390/molecules24132355