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Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’
Seven novel norcycloartane glycosides, maryloside A–G (1–7), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651146/ https://www.ncbi.nlm.nih.gov/pubmed/31323985 http://dx.doi.org/10.3390/molecules24132504 |
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| author | Yoneyama, Tatsuro Iseki, Kanako Noji, Masaaki Imagawa, Hiroshi Hashimoto, Toshihiro Kawano, Sachiko Baba, Masaki Kashiwada, Yoshiki Yahagi, Tadahiro Matsuzaki, Keiichi Umeyama, Akemi |
| author_facet | Yoneyama, Tatsuro Iseki, Kanako Noji, Masaaki Imagawa, Hiroshi Hashimoto, Toshihiro Kawano, Sachiko Baba, Masaki Kashiwada, Yoshiki Yahagi, Tadahiro Matsuzaki, Keiichi Umeyama, Akemi |
| author_sort | Yoneyama, Tatsuro |
| collection | PubMed |
| description | Seven novel norcycloartane glycosides, maryloside A–G (1–7), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds (1–6 and 8) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, 1 and 3 exhibited moderate activity. |
| format | Online Article Text |
| id | pubmed-6651146 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-66511462019-08-07 Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’ Yoneyama, Tatsuro Iseki, Kanako Noji, Masaaki Imagawa, Hiroshi Hashimoto, Toshihiro Kawano, Sachiko Baba, Masaki Kashiwada, Yoshiki Yahagi, Tadahiro Matsuzaki, Keiichi Umeyama, Akemi Molecules Article Seven novel norcycloartane glycosides, maryloside A–G (1–7), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds (1–6 and 8) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, 1 and 3 exhibited moderate activity. MDPI 2019-07-09 /pmc/articles/PMC6651146/ /pubmed/31323985 http://dx.doi.org/10.3390/molecules24132504 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Yoneyama, Tatsuro Iseki, Kanako Noji, Masaaki Imagawa, Hiroshi Hashimoto, Toshihiro Kawano, Sachiko Baba, Masaki Kashiwada, Yoshiki Yahagi, Tadahiro Matsuzaki, Keiichi Umeyama, Akemi Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’ |
| title | Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’ |
| title_full | Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’ |
| title_fullStr | Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’ |
| title_full_unstemmed | Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’ |
| title_short | Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’ |
| title_sort | marylosides a-g, norcycloartane glycosides from leaves of cymbidium great flower ‘marylaurencin’ |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651146/ https://www.ncbi.nlm.nih.gov/pubmed/31323985 http://dx.doi.org/10.3390/molecules24132504 |
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