CRISPR-Cas9 Mediated TSPO Gene Knockout alters Respiration and Cellular Metabolism in Human Primary Microglia Cells

The 18 kDa translocator protein (TSPO) is an evolutionary conserved cholesterol binding protein localized in the outer mitochondrial membrane. It has been implicated in the regulation of various cellular processes including oxidative stress, proliferation, apoptosis, and steroid hormone biosynthesis...

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Detalles Bibliográficos
Autores principales: Milenkovic, Vladimir M., Slim, Dounia, Bader, Stefanie, Koch, Victoria, Heinl, Elena-Sofia, Alvarez-Carbonell, David, Nothdurfter, Caroline, Rupprecht, Rainer, Wetzel, Christian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651328/
https://www.ncbi.nlm.nih.gov/pubmed/31323920
http://dx.doi.org/10.3390/ijms20133359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651328/
https://www.ncbi.nlm.nih.gov/pubmed/31323920
http://dx.doi.org/10.3390/ijms20133359

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