Fine-Tuning the Activation Mode of an 1,3-Indandione-Based Ruthenium(II)-Cymene Half-Sandwich Complex by Variation of Its Leaving Group

Fine-tuning of the properties of a recently reported 1,3-indandione-based organoruthenium complex is attempted to optimize the stability under physiological conditions. Previous work has shown its capacity of inhibiting topoisomerase IIα; however, fast aquation leads to undesired reactions and ligan...

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Detalles Bibliográficos
Autores principales: Mokesch, Stephan, Schwarz, Daniela, Hejl, Michaela, Klose, Matthias H. M., Roller, Alexander, Jakupec, Michael A., Kandioller, Wolfgang, Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651387/
https://www.ncbi.nlm.nih.gov/pubmed/31252521
http://dx.doi.org/10.3390/molecules24132373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651387/
https://www.ncbi.nlm.nih.gov/pubmed/31252521
http://dx.doi.org/10.3390/molecules24132373

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