Cargando…

Photosensitive Melanopsin-Containing Retinal Ganglion Cells in Health and Disease: Implications for Circadian Rhythms

Melanopsin-containing retinal ganglion cells (mRGCs) represent a third class of retinal photoreceptors involved in regulating the pupillary light reflex and circadian photoentrainment, among other things. The functional integrity of the circadian system and melanopsin cells is an essential component...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lax, Pedro, Ortuño-Lizarán, Isabel, Maneu, Victoria, Vidal-Sanz, Manuel, Cuenca, Nicolás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651433/ https://www.ncbi.nlm.nih.gov/pubmed/31261700 http://dx.doi.org/10.3390/ijms20133164

Ejemplares similares

Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson’s disease
por: Ortuño-Lizarán, Isabel, et al.
Publicado: (2018)

Melanopsin expression is an indicator of the well-being of melanopsin-expressing retinal ganglion cells but not of their viability
por: Agudo-Barriuso, Marta, et al.
Publicado: (2016)

THE INJURY RESISTANT ABILITY OF MELANOPSIN-EXPRESSING INTRINSICALLY PHOTOSENSITIVE RETINAL GANGLION CELLS
por: Cui, Q., et al.
Publicado: (2014)

Current and future therapeutic strategies for the treatment of retinal neurodegenerative diseases
por: Maneu, Victoria, et al.
Publicado: (2021)

Neuroprotective Effects of Tauroursodeoxicholic Acid Involves Vascular and Glial Changes in Retinitis Pigmentosa Model
por: Fernández-Sánchez, Laura, et al.
Publicado: (2022)

Loss of Melanopsin-Expressing Ganglion Cell Subtypes and Dendritic Degeneration in the Aging Human Retina
por: Esquiva, Gema, et al.
Publicado: (2017)

Melanopsin retinal ganglion cell loss and circadian dysfunction in Alzheimer's disease (Review)
por: FENG, RUIQI, et al.
Publicado: (2016)

The Absence of Toll-Like Receptor 4 Mildly Affects the Structure and Function in the Adult Mouse Retina
por: Noailles, Agustina, et al.
Publicado: (2019)

Deleterious Effect of NMDA Plus Kainate on the Inner Retinal Cells and Ganglion Cell Projection of the Mouse
por: Calvo, Estrella, et al.
Publicado: (2020)

The Circadian Response of Intrinsically Photosensitive Retinal Ganglion Cells
por: Zele, Andrew J., et al.
Publicado: (2011)

Light-Induced Fos Expression in Intrinsically Photosensitive Retinal Ganglion Cells in Melanopsin Knockout (Opn4(−/−)) Mice
por: Pickard, Gary E., et al.
Publicado: (2009)

M1 Intrinsically Photosensitive Retinal Ganglion Cells Integrate Rod and Melanopsin Inputs to Signal in Low Light
por: Lee, Seul Ki, et al.
Publicado: (2019)

Systemic inflammation induced by lipopolysaccharide aggravates inherited retinal dystrophy
por: Noailles, Agustina, et al.
Publicado: (2018)

Prph2 knock-in mice recapitulate human central areolar choroidal dystrophy retinal degeneration and exhibit aberrant synaptic remodeling and microglial activation
por: Ruiz-Pastor, María José, et al.
Publicado: (2023)

Melanopsin-mediated optical entrainment regulates circadian rhythms in vertebrates
por: Pan, Deng, et al.
Publicado: (2023)

Low-Intensity Blue Light Exposure Reduces Melanopsin Expression in Intrinsically Photosensitive Retinal Ganglion Cells and Damages Mitochondria in Retinal Ganglion Cells in Wistar Rats
por: Ziółkowska, Natalia, et al.
Publicado: (2023)

G-Protein Coupled Receptor Kinase 2 Minimally Regulates Melanopsin Activity in Intrinsically Photosensitive Retinal Ganglion Cells
por: Sexton, Timothy J., et al.
Publicado: (2015)

Photon capture and signalling by melanopsin retinal ganglion cells
por: Do, Michael Tri H., et al.
Publicado: (2008)

Melanopsin retinal ganglion cell loss in Alzheimer disease
por: La Morgia, Chiara, et al.
Publicado: (2015)

Targeted Destruction of Photosensitive Retinal Ganglion Cells with a Saporin Conjugate Alters the Effects of Light on Mouse Circadian Rhythms
por: Göz, Didem, et al.
Publicado: (2008)

Starburst amacrine cells, involved in visual motion perception, lose their synaptic input from dopaminergic amacrine cells and degenerate in Parkinson’s disease patients
por: Sánchez-Sáez, Xavier, et al.
Publicado: (2023)

Correction: Starburst amacrine cells, involved in visual motion perception, lose their synaptic input from dopaminergic amacrine cells and degenerate in Parkinson’s disease patients
por: Sánchez‑Sáez, Xavier, et al.
Publicado: (2023)

The Effect of Pupil Size on Stimulation of the Melanopsin Containing Retinal Ganglion Cells, as Evaluated by Monochromatic Pupillometry
por: Nissen, Claus, et al.
Publicado: (2012)

Multimodal investigation of melanopsin retinal ganglion cells in Alzheimer's disease
por: La Morgia, Chiara, et al.
Publicado: (2023)

Persistent inflammatory state after photoreceptor loss in an animal model of retinal degeneration
por: Noailles, Agustina, et al.
Publicado: (2016)

Natural Compounds from Saffron and Bear Bile Prevent Vision Loss and Retinal Degeneration
por: Fernández-Sánchez, Laura, et al.
Publicado: (2015)

The Roles of Rods, Cones, and Melanopsin in Photoresponses of M4 Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) and Optokinetic Visual Behavior
por: Schroeder, Melanie M., et al.
Publicado: (2018)

Melanopsin Retinal Ganglion Cells and Pupil: Clinical Implications for Neuro-Ophthalmology
por: La Morgia, Chiara, et al.
Publicado: (2018)

Distinct responses of cones and melanopsin-expressing retinal ganglion cells in the human electroretinogram
por: Fukuda, Yumi, et al.
Publicado: (2012)

Melanopsin Ganglion Cells Are the Most Resistant Retinal Ganglion Cell Type to Axonal Injury in the Rat Retina
por: Pérez de Sevilla Müller, Luis, et al.
Publicado: (2014)

Retinal Ganglion Cells and Circadian Rhythms in Alzheimer’s Disease, Parkinson’s Disease, and Beyond
por: La Morgia, Chiara, et al.
Publicado: (2017)

Gradual Increase in Environmental Light Intensity Induces Oxidative Stress and Inflammation and Accelerates Retinal Neurodegeneration
por: Kutsyr, Oksana, et al.
Publicado: (2020)

Visual Disfunction due to the Selective Effect of Glutamate Agonists on Retinal Cells
por: Milla-Navarro, Santiago, et al.
Publicado: (2021)

Chemogenetic Activation of Melanopsin Retinal Ganglion Cells Induces Signatures of Arousal and/or Anxiety in Mice
por: Milosavljevic, Nina, et al.
Publicado: (2016)

Intrinsically photosensitive retinal ganglion cells in glaucoma
por: Gao, Jingyi, et al.
Publicado: (2022)

THU315 Sleep And Circadian Regulation, And Intrinsically Photosensitive Retinal Ganglion Cells Function In Diabetic Retinopathy
por: Reutrakul, Sirimon, et al.
Publicado: (2023)

Cellular and molecular alterations in neurons and glial cells in inherited retinal degeneration
por: Martínez-Gil, Natalia, et al.
Publicado: (2022)

Melanopsin(+)RGCs Are fully Resistant to NMDA-Induced Excitotoxicity
por: Vidal-Villegas, Beatriz, et al.
Publicado: (2019)

Inherited Retinal Dystrophies: Role of Oxidative Stress and Inflammation in Their Physiopathology and Therapeutic Implications
por: Pinilla, Isabel, et al.
Publicado: (2022)

M1-Type, but Not M4-Type, Melanopsin Ganglion Cells Are Physiologically Tuned to the Central Circadian Clock
por: Stinchcombe, Adam R., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_q5clrptocicqkrefugahv2jecq