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Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point

The repetitive telomeric DNA at chromosome ends is protected from unwanted repair by telomere-associated proteins, which form the shelterin complex in mammals. Recent works have provided new insights into the mechanisms of how human shelterin assembles and recruits telomerase to telomeres. Inhibitio...

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Detalles Bibliográficos
Autores principales: Veverka, Pavel, Janovič, Tomáš, Hofr, Ctirad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651453/
https://www.ncbi.nlm.nih.gov/pubmed/31261825
http://dx.doi.org/10.3390/ijms20133186