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Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point
The repetitive telomeric DNA at chromosome ends is protected from unwanted repair by telomere-associated proteins, which form the shelterin complex in mammals. Recent works have provided new insights into the mechanisms of how human shelterin assembles and recruits telomerase to telomeres. Inhibitio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651453/ https://www.ncbi.nlm.nih.gov/pubmed/31261825 http://dx.doi.org/10.3390/ijms20133186 |