Cargando…

Reactive Oxygen Species Are Key Mediators of Demyelination in Canine Distemper Leukoencephalitis but not in Theiler’s Murine Encephalomyelitis

(1) Background: Canine distemper virus (CDV)-induced demyelinating leukoencephalitis (CDV-DL) in dogs and Theiler’s murine encephalomyelitis (TME) virus (TMEV)-induced demyelinating leukomyelitis (TMEV-DL) are virus-induced demyelinating conditions mimicking Multiple Sclerosis (MS). Reactive oxygen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Attig, Friederike, Spitzbarth, Ingo, Kalkuhl, Arno, Deschl, Ulrich, Puff, Christina, Baumgärtner, Wolfgang, Ulrich, Reiner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651464/ https://www.ncbi.nlm.nih.gov/pubmed/31262031 http://dx.doi.org/10.3390/ijms20133217

Ejemplares similares

Transcriptional Changes in Canine Distemper Virus-Induced Demyelinating Leukoencephalitis Favor a Biphasic Mode of Demyelination
por: Ulrich, Reiner, et al.
Publicado: (2014)

Immunohistochemical and transcriptome analyses indicate complex breakdown of axonal transport mechanisms in canine distemper leukoencephalitis
por: Spitzbarth, Ingo, et al.
Publicado: (2016)

New Aspects of the Pathogenesis of Canine Distemper Leukoencephalitis
por: Lempp, Charlotte, et al.
Publicado: (2014)

Neurotoxic potential of reactive astrocytes in canine distemper demyelinating leukoencephalitis
por: Klemens, J., et al.
Publicado: (2019)

Accumulation of Extracellular Matrix in Advanced Lesions of Canine Distemper Demyelinating Encephalitis
por: Seehusen, Frauke, et al.
Publicado: (2016)

Reduced angiogenic gene expression in morbillivirus‐triggered oncolysis in a translational model for histiocytic sarcoma
por: Pfankuche, Vanessa Maria, et al.
Publicado: (2016)

Machine learning approach identifies new pathways associated with demyelination in a viral model of multiple sclerosis
por: Ulrich, Reiner, et al.
Publicado: (2010)

Transcriptomic Meta-Analysis of Multiple Sclerosis and Its Experimental Models
por: Raddatz, Barbara B. R., et al.
Publicado: (2014)

Persistent Morbillivirus Infection Leads to Altered Cortactin Distribution in Histiocytic Sarcoma Cells with Decreased Cellular Migration Capacity
por: Pfankuche, Vanessa Maria, et al.
Publicado: (2016)

Demyelination in canine distemper encephalomyelitis: An ultrastructural analysis
por: Sumummers, Brian A., et al.
Publicado: (1987)

Morphologic, phenotypic, and transcriptomic characterization of classically and alternatively activated canine blood-derived macrophages in vitro
por: Heinrich, Franziska, et al.
Publicado: (2017)

Astrocyte depletion alters extracellular matrix composition in the demyelinating phase of Theiler’s murine encephalomyelitis
por: Allnoch, Lisa, et al.
Publicado: (2022)

Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease
por: Li, Lin, et al.
Publicado: (2015)

IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler’s Murine Encephalomyelitis Viruses
por: Bühler, Melanie, et al.
Publicado: (2022)

Differential transcription of matrix-metalloproteinase genes in primary mouse astrocytes and microglia infected with Theiler’s murine encephalomyelitis virus
por: Kumnok, Jirawat, et al.
Publicado: (2008)

Pathogenesis of Theiler's Murine Encephalomyelitis Virus
por: Yamada, Masahito, et al.
Publicado: (1991)

Comparison of Reported Spinal Cord Lesions in Progressive Multiple Sclerosis with Theiler’s Murine Encephalomyelitis Virus Induced Demyelinating Disease
por: Leitzen, Eva, et al.
Publicado: (2019)

Facets of Theiler’s Murine Encephalomyelitis Virus-Induced Diseases: An Update
por: Gerhauser, Ingo, et al.
Publicado: (2019)

ASC- and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler’s murine encephalomyelitis virus
por: Li, Dandan, et al.
Publicado: (2023)

Monoclonal antibody to Theiler's murine encephalomyelitis virus defines a determinant on myelin and oligodendrocytes, and augments demyelination in experimental allergic encephalomyelitis
Publicado: (1990)

Characterization of Ribosomal Frameshifting in Theiler's Murine Encephalomyelitis Virus
por: Finch, Leanne K., et al.
Publicado: (2015)

Effect of Siponimod on Brain and Spinal Cord Imaging Markers of Neurodegeneration in the Theiler’s Murine Encephalomyelitis Virus Model of Demyelination
por: Pol, Suyog, et al.
Publicado: (2023)

IFNAR signaling of neuroectodermal cells is essential for the survival of C57BL/6 mice infected with Theiler’s murine encephalomyelitis virus
por: Bühler, Melanie, et al.
Publicado: (2023)

Theiler's Murine Encephalomyelitis Virus as a Vaccine Candidate for Immunotherapy
por: Pavelko, Kevin D., et al.
Publicado: (2011)

TDP-43 proteinopathy in Theiler’s murine encephalomyelitis virus infection
por: Masaki, Katsuhisa, et al.
Publicado: (2019)

Viral Oncolysis — Can Insights from Measles Be Transferred to Canine Distemper Virus?
por: Lapp, Stefanie, et al.
Publicado: (2014)

Primary demyelination in experimental canine distemper virus induced encephalomyelitis in gnotobiotic dogs: Sequential immunologic and morphologic findings
por: Higgins, R. J., et al.
Publicado: (1982)

Oxidative Stress in Canine Histiocytic Sarcoma Cells Induced by an Infection with Canine Distemper Virus Led to a Dysregulation of HIF-1α Downstream Pathway Resulting in a Reduced Expression of VEGF-B In Vitro
por: Armando, Federico, et al.
Publicado: (2020)

Innate immune response induced by Theiler's murine encephalomyelitis virus infection
por: Kim, Byung S., et al.
Publicado: (2005)

Intratumoral Canine Distemper Virus Infection Inhibits Tumor Growth by Modulation of the Tumor Microenvironment in a Murine Xenograft Model of Canine Histiocytic Sarcoma
por: Armando, Federico, et al.
Publicado: (2021)

Distemper in a Dolphin
por: Wohlsein, Peter, et al.
Publicado: (2007)

Cannabidiol reduces seizures following CNS infection with Theiler's murine encephalomyelitis virus
por: Patel, Dipan C., et al.
Publicado: (2019)

Gut dysbiosis and neuroimmune responses to brain infection with Theiler’s murine encephalomyelitis virus
por: Carrillo-Salinas, F. J., et al.
Publicado: (2017)

Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus
por: Napthine, Sawsan, et al.
Publicado: (2019)

Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis
por: Machado, Gisele F., et al.
Publicado: (2013)

Immune mechanisms of Theiler's virus-induced demyelination
por: Kim, Byung Suk, et al.
Publicado: (1999)

Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease(): III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination
por: Miller, Stephen D., et al.
Publicado: (1990)

Early and widespread injury of astrocytes in the absence of demyelination in acute haemorrhagic leukoencephalitis
por: Robinson, Christopher A, et al.
Publicado: (2014)

Comparison of Theiler’s Murine Encephalomyelitis Virus Induced Spinal Cord and Peripheral Nerve Lesions Following Intracerebral and Intraspinal Infection
por: Jin, Wen, et al.
Publicado: (2019)

Ovalbumin-specific CD4(+) and CD8(+) T cells contribute to different susceptibility for Theiler’s murine encephalomyelitis virus persistence
por: Wannemacher, Rouven, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9tcouvcaq0fd40o82c3qamjt9n