Cargando…

Pro-Apoptotic Effect of Grape Seed Extract on MCF-7 Involves Transient Increase of Gap Junction Intercellular Communication and Cx43 Up-Regulation: A Mechanism of Chemoprevention

Growing evidence suggests dietary antioxidants reduce the risk of several cancers. Grape seeds extracts (GSE) are a rich source of polyphenols known to have antioxidant, chemopreventive and anticancer properties. Herein, we investigated the in vitro effects and putative action mechanisms of a grape...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leone, Antonella, Longo, Cristiano, Gerardi, Carmela, Trosko, James E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651466/ https://www.ncbi.nlm.nih.gov/pubmed/31269652 http://dx.doi.org/10.3390/ijms20133244

Ejemplares similares

Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication
por: Forster, Tobias, et al.
Publicado: (2014)

Modulation of Cx43 and Gap Junctional Intercellular Communication by Androstenedione in Rat Polycystic Ovary and Granulosa Cells in vitro
por: Talhouk, Rabih, et al.
Publicado: (2012)

Tumor Necrosis Factor-Alpha Disrupts Cx43-Mediated Corneal Endothelial Gap Junction Intercellular Communication
por: Meng, Jufeng, et al.
Publicado: (2022)

Regulation of Cx43 Gap Junction Intercellular Communication by Bruton’s Tyrosine Kinase and Interleukin-2-Inducible T-Cell Kinase
por: Basu, Ishika, et al.
Publicado: (2023)

All-trans retinoic acid restores gap junctional intercellular communication between oral cancer cells with upregulation of Cx32 and Cx43 expressions in vitro
por: Wang, Juan, et al.
Publicado: (2013)

Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover
por: Solan, Joell L., et al.
Publicado: (2020)

Cancer Prevention and Therapy of Two Types of Gap Junctional Intercellular Communication–Deficient “Cancer Stem Cell”
por: Trosko, James E.
Publicado: (2019)

Correlations of Differentially Expressed Gap Junction Connexins Cx26, Cx30, Cx32, Cx43 and Cx46 with Breast Cancer Progression and Prognosis
por: Teleki, Ivett, et al.
Publicado: (2014)

Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels
por: Desplantez, Thomas
Publicado: (2017)

Altered Expression of Glial Gap Junction Proteins Cx43, Cx30, and Cx47 in the 5XFAD Model of Alzheimer’s Disease
por: Angeli, Stella, et al.
Publicado: (2020)

Ultrastructure of gap junction and Cx43 expression in gastric cancer tissues of the patients
por: Li, Chun-Hui, et al.
Publicado: (2020)

Modulated gap junctional intercellular communication as a biomarker of PAH epigenetic toxicity: structure-function relationship.
por: Upham, B L, et al.
Publicado: (1998)

Levonorgestrel Inhibits Human Endometrial Cell Proliferation through the Upregulation of Gap Junctional Intercellular Communication via the Nuclear Translocation of Ser255 Phosphorylated Cx43
por: Zhao, Xiaomiao, et al.
Publicado: (2015)

The role of the Cx43/Cx45 gap junction voltage gating on wave propagation and arrhythmogenic activity in cardiac tissue
por: Maciunas, Kestutis, et al.
Publicado: (2023)

Intracellular spermine prevents acid-induced uncoupling of Cx43 gap junction channels
por: Skatchkov, Serguei N., et al.
Publicado: (2015)

Impaired Cx43 gap junction endocytosis causes morphological and functional defects in zebrafish
por: Hyland, Caitlin, et al.
Publicado: (2021)

Evolution of Microbial Quorum Sensing to Human Global Quorum Sensing: An Insight into How Gap Junctional Intercellular Communication Might Be Linked to the Global Metabolic Disease Crisis
por: Trosko, James E.
Publicado: (2016)

Bay or baylike regions of polycyclic aromatic hydrocarbons were potent inhibitors of Gap junctional intercellular communication.
por: Weis, L M, et al.
Publicado: (1998)

Inhibition of Gap Junctional Intercellular Communication Upregulates Pluripotency Gene Expression in Endogenous Pluripotent Muse Cells
por: Hatabi, Khaled, et al.
Publicado: (2022)

Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43
por: Boogerd, C. J. J., et al.
Publicado: (2011)

Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells
por: Soares, Ana Rosa, et al.
Publicado: (2015)

Aberrant Expression of Cx43 Is Associated with the Peritoneal Metastasis of Gastric Cancer and Cx43-Mediated Gap Junction Enhances Gastric Cancer Cell Diapedesis from Peritoneal Mesothelium
por: Tang, Bo, et al.
Publicado: (2013)

Desmin Correlated with Cx43 May Facilitate Intercellular Electrical Coupling during Chronic Heart Failure
por: Cao, Junxian, et al.
Publicado: (2021)

Marine sponge depsipeptide increases gap junction length in HTC cells transfected with Cx43–GFP
por: Rangel, Marisa, et al.
Publicado: (2010)

HPV16 E6 Controls the Gap Junction Protein Cx43 in Cervical Tumour Cells
por: Sun, Peng, et al.
Publicado: (2015)

Corrigendum: Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells
por: Soares, Ana Rosa, et al.
Publicado: (2015)

Regulation of gap junction conductance by calcineurin through Cx43 phosphorylation: implications for action potential conduction
por: Jabr, Rita I, et al.
Publicado: (2016)

Evaluation of Cx43 Gap Junction Inhibitors Using a Quantitative Structure-Activity Relationship Model
por: Matusevičiūtė, Ramona, et al.
Publicado: (2023)

BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution
por: Chai, Chengyan, et al.
Publicado: (2023)

Inhibition of gap junctional intercellular communication in normal human breast epithelial cells after treatment with pesticides, PCBs, and PBBs, alone or in mixtures.
por: Kang, K S, et al.
Publicado: (1996)

The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
por: Fumagalli, Amos, et al.
Publicado: (2020)

Cx43 phosphorylation on S279/282 and intercellular communication are regulated by IP(3)/IP(3) receptor signaling
por: Kang, Man, et al.
Publicado: (2014)

Fenofibrate Interferes with the Diapedesis of Lung Adenocarcinoma Cells through the Interference with Cx43/EGF-Dependent Intercellular Signaling
por: Piwowarczyk, Katarzyna, et al.
Publicado: (2018)

Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis
por: Fong, John T., et al.
Publicado: (2013)

Diabetes Increases Cryoinjury Size with Associated Effects on Cx43 Gap Junction Function and Phosphorylation in the Mouse Heart
por: Palatinus, Joseph A., et al.
Publicado: (2016)

Enhanced expression of Cx43 and gap junction communication in vascular smooth muscle cells of spontaneously hypertensive rats
por: Wang, Li-Jie, et al.
Publicado: (2016)

Cx43-Gap Junctions Accumulate at the Cytotoxic Immunological Synapse Enabling Cytotoxic T Lymphocyte Melanoma Cell Killing
por: Hofmann, Francisca, et al.
Publicado: (2019)

Inhibition of gap junction composed of Cx43 prevents against acute kidney injury following liver transplantation
por: Yuan, Dongdong, et al.
Publicado: (2019)

Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM
por: Lee, Hyuk-Joon, et al.
Publicado: (2023)

Plasmalogens Regulate Retinal Connexin 43 Expression and Müller Glial Cells Gap Junction Intercellular Communication and Migration
por: Karadayi, Rémi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_34vponaidachplp9vjom55j0r0