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IL-13 Impairs Tight Junctions in Airway Epithelia

Interleukin-13 (IL-13) drives symptoms in asthma with high levels of T-helper type 2 cells (T(h)2-cells). Since tight junctions (TJ) constitute the epithelial diffusion barrier, we investigated the effect of IL-13 on TJ in human tracheal epithelial cells. We observed that IL-13 increases paracellula...

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Detalles Bibliográficos
Autores principales:	Schmidt, Hanna, Braubach, Peter, Schilpp, Carolin, Lochbaum, Robin, Neuland, Kathrin, Thompson, Kristin, Jonigk, Danny, Frick, Manfred, Dietl, Paul, Wittekindt, Oliver H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651493/ https://www.ncbi.nlm.nih.gov/pubmed/31262043 http://dx.doi.org/10.3390/ijms20133222

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