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Deletion of OGG1 Results in a Differential Signature of Oxidized Purine Base Damage in mtDNA Regions

Mitochondrial oxidative stress accumulates with aging and age-related diseases and induces alterations in mitochondrial DNA (mtDNA) content. Since mtDNA qualitative alterations are also associated with aging, repair of mtDNA damage is of great importance. The most relevant form of DNA repair in this...

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Detalles Bibliográficos
Autores principales:	Chimienti, Guglielmina, Pesce, Vito, Fracasso, Flavio, Russo, Francesco, de Souza-Pinto, Nadja Cristhina, Bohr, Vilhelm A., Lezza, Angela Maria Serena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651574/ https://www.ncbi.nlm.nih.gov/pubmed/31284385 http://dx.doi.org/10.3390/ijms20133302

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