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Synthesis, Molecular Docking Analysis, and Carbonic Anhydrase Inhibitory Evaluations of Benzenesulfonamide Derivatives Containing Thiazolidinone

To find novel human carbonic anhydrase (hCA) inhibitors, we synthesized thirteen compounds by combining thiazolidinone with benzenesulfonamide. The result of the X-ray single-crystal diffraction experiment confirmed the configuration of this class of compounds. The enzyme inhibition assays against h...

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Detalles Bibliográficos
Autores principales: Zhang, Zuo-Peng, Yin, Ze-Fa, Li, Jia-Yue, Wang, Zhi-Peng, Wu, Qian-Jie, Wang, Jian, Liu, Yang, Cheng, Mao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651801/
https://www.ncbi.nlm.nih.gov/pubmed/31262068
http://dx.doi.org/10.3390/molecules24132418