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5-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift

The stimulation of the AMP-activated kinase (AMPK) by 5-amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) has been associated with antihyperalgesia and the inhibition of nociceptive signaling in the spinal cord in models of paw inflammation. The attenuated nociception comes along with a stro...

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Detalles Bibliográficos
Autores principales:	Martin, Lisa Maria, Möller, Moritz, Weiss, Ulrike, Russe, Otto Quintus, Scholich, Klaus, Pierre, Sandra, Geisslinger, Gerd, Niederberger, Ellen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651813/ https://www.ncbi.nlm.nih.gov/pubmed/31269729 http://dx.doi.org/10.3390/ijms20133255

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