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Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells

Low fruit and vegetable consumption and high saturated fat consumption causes elevated circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, oxysterols form that bind and activate the liver X receptors (LXRs). Oxysterols halt breast cancer cell proliferation but...

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Detalles Bibliográficos
Autores principales: Hutchinson, Samantha A., Lianto, Priscilia, Moore, J. Bernadette, Hughes, Thomas A., Thorne, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651815/
https://www.ncbi.nlm.nih.gov/pubmed/31269628
http://dx.doi.org/10.3390/ijms20133241