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In Silico Prediction of PAMPA Effective Permeability Using a Two-QSAR Approach

Oral administration is the preferred and predominant route of choice for medication. As such, drug absorption is one of critical drug metabolism and pharmacokinetics (DM/PK) parameters that should be taken into consideration in the process of drug discovery and development. The cell-free in vitro pa...

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Detalles Bibliográficos
Autores principales: Chi, Cheng-Ting, Lee, Ming-Han, Weng, Ching-Feng, Leong, Max K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651837/
https://www.ncbi.nlm.nih.gov/pubmed/31261723
http://dx.doi.org/10.3390/ijms20133170

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