Immunization of Rabbits with Recombinant Human Cytomegalovirus Trimeric versus Monomeric gH/gL Protein Elicits Markedly Higher Titers of Antibody and Neutralization Activity

Congenital human cytomegalovirus (HCMV) infection and HCMV infection of immunosuppressed patients cause significant morbidity and mortality, and vaccine development against HCMV is a major public health priority. HCMV envelope glycoproteins gB, gH, and gL, which constitute the core fusion machinery,...

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Detalles Bibliográficos
Autores principales: Cui, Xinle, Cao, Zhouhong, Wang, Shuishu, Flora, Michael, Adler, Stuart P., McVoy, Michael A., Snapper, Clifford M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651862/
https://www.ncbi.nlm.nih.gov/pubmed/31261659
http://dx.doi.org/10.3390/ijms20133158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651862/
https://www.ncbi.nlm.nih.gov/pubmed/31261659
http://dx.doi.org/10.3390/ijms20133158

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