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Next-generation sequencing using microfluidic PCR enrichment for molecular autopsy

BACKGROUND: We aimed to determine the mutation yield and clinical applicability of “molecular autopsy” following sudden arrhythmic death syndrome (SADS) by validating and utilizing low-cost high-throughput technologies: Fluidigm Access Array PCR-enrichment with Illumina HiSeq 2000 next generation se...

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Detalles Bibliográficos
Autores principales:	Raju, Hariharan, Ware, James S., Skinner, Jonathan R., Hedley, Paula L., Arno, Gavin, Love, Donald R., van der Werf, Christian, Tfelt-Hansen, Jacob, Winkel, Bo Gregers, Cohen, Marta C., Li, Xinzhong, John, Shibu, Sharma, Sanjay, Jeffery, Steve, Wilde, Arthur A. M., Christiansen, Michael, Sheppard, Mary N., Behr, Elijah R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651896/ https://www.ncbi.nlm.nih.gov/pubmed/31337358 http://dx.doi.org/10.1186/s12872-019-1154-8

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