Deterioration in Clinical Status Is Not Enough to Suspend Eculizumab: A Genetic Complement-Mediated Atypical Hemolytic Uremic Syndrome Case Report

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. Mutations in CFI gene coding for complement regulation factors and in THBD gene coding for endothelial cell receptor thrombomodulin could predispose to th...

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Detalles Bibliográficos
Autores principales: Calvaruso, Luca, Naticchia, Alessandro, Ferraro, Pietro Manuel, Vischini, Gisella, Costanzi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652041/
https://www.ncbi.nlm.nih.gov/pubmed/31360562
http://dx.doi.org/10.1155/2019/9264824

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