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Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia

BACKGROUND: Th17/Treg balance skews towards Th17 in ITP patient. IRF4 has been highlighted for its close relationship to the immunosuppressive function of Treg cells and the IL-17 synthesis in CD4(+) T cells. This study was aimed at examining the effects of IRF4 to the Th17/Treg cells in patients wi...

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Detalles Bibliográficos
Autores principales:	Tang, Meiwen, Cheng, Luya, Li, Feng, Wu, Boting, Chen, Pu, Zhan, Yanxia, Hua, Fanli, Min, Zhihui, Ke, Yang, Liu, Chanjuan, Yuan, Ling, Sun, Lihua, Chen, Hao, Ji, Lili, Cheng, Yunfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652070/ https://www.ncbi.nlm.nih.gov/pubmed/31380412 http://dx.doi.org/10.1155/2019/1050285

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