Cargando…

Convulsive Stress Mimics Brain Hypoxia and Promotes the P-Glycoprotein (P-gp) and Erythropoietin Receptor Overexpression. Recombinant Human Erythropoietin Effect on P-gp Activity

Erythropoietin (EPO) is not only a hormone that promotes erythropoiesis but also has a neuroprotective effect on neurons attributed to its known anti-apoptotic action. Previously, our group has demonstrated that recombinant-human EPO (rHu-EPO) can protect neurons and recovery motor activity in a che...

Descripción completa

Detalles Bibliográficos
Autores principales:	Merelli, Amalia, Ramos, Alberto Javier, Lazarowski, Alberto, Auzmendi, Jeronimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652211/ https://www.ncbi.nlm.nih.gov/pubmed/31379495 http://dx.doi.org/10.3389/fnins.2019.00750

Ejemplares similares

Pilocarpine-Induced Status Epilepticus Is Associated with P-Glycoprotein Induction in Cardiomyocytes, Electrocardiographic Changes, and Sudden Death
por: Auzmendi, Jerónimo, et al.
Publicado: (2018)

P glycoprotein (P-gp) and drug resistance--time for reappraisal?
por: Kaye, S. B.
Publicado: (1993)

Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug–Drug Interaction Studies
por: Elmeliegy, Mohamed, et al.
Publicado: (2020)

Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition
por: Dewanjee, Saikat, et al.
Publicado: (2017)

The equilibrium and kinetic drug binding properties of the mouse P-gp1a and P-gp1b P-glycoproteins are similar
por: Taylor, J C, et al.
Publicado: (1999)

Myocardial Iron Overload in an Experimental Model of Sudden Unexpected Death in Epilepsy
por: Akyuz, Enes, et al.
Publicado: (2021)

P-gp and taxanes
por: Hendrikx, Jeroen J.M.A., et al.
Publicado: (2014)

Cannabidiol (CBD) Alters the Functionality of Neutrophils (PMN). Implications in the Refractory Epilepsy Treatment
por: Gómez, Claudia Taborda, et al.
Publicado: (2021)

Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: Stability and pH effects
por: Harrison, Joseph S, et al.
Publicado: (2011)

Comparison of Oral Recombinant Erythropoietin and Subcutaneous Recombinant Erythropoietin in Prevention of Anemia of Prematurity
por: Saeidi, R, et al.
Publicado: (2012)

Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions
por: Auzmendi, Jerónimo, et al.
Publicado: (2020)

G.P. and Hospital Medicine
por: Ractliffe, Donald
Publicado: (1988)

Dexamethasone mimics aspects of physiological acclimatization to 8 hours of hypoxia but suppresses plasma erythropoietin
por: Liu, Chun, et al.
Publicado: (2013)

Erythropoietin mimics the acute phase response in critical illness
por: Elliot, John Michael, et al.
Publicado: (2003)

Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level?
por: Czornyj, Liliana, et al.
Publicado: (2021)

Recombinant Erythropoietin in Humans Has a Prolonged Effect on Circulating Erythropoietin Isoform Distribution
por: Aachmann-Andersen, Niels Jacob, et al.
Publicado: (2014)

The Clinical Impact of Recombinant Human Erythropoietin
por: Muirhead, N
Publicado: (1997)

Probing the Allosteric Modulation of P-Glycoprotein: A Medicinal Chemistry Approach Toward the Identification of Noncompetitive P-Gp Inhibitors
por: Bonito, Cátia A., et al.
Publicado: (2023)

Chemical biology fluorescent tools for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells
por: Daumar, Pierre, et al.
Publicado: (2023)

Hypoxia-inducible erythropoietin expression: details matter
por: Kietzmann, Thomas
Publicado: (2020)

Early Gabapentin Treatment during the Latency Period Increases Convulsive Threshold, Reduces Microglial Activation and Macrophage Infiltration in the Lithium-Pilocarpine Model of Epilepsy
por: Rossi, Alicia, et al.
Publicado: (2017)

Mini-P-gp and P-gp Co-Expression in Brown Trout Erythrocytes: A Prospective Blood Biomarker of Aquatic Pollution
por: Valton, Emeline, et al.
Publicado: (2015)

Uncoupling GP1 and GP2 expression in the Lassa virus glycoprotein complex: implications for GP1 ectodomain shedding
por: Illick, Megan M, et al.
Publicado: (2008)

Pharmacokinetics of PEGylated Recombinant Human Erythropoietin in Rats
por: Cao, Xiaohan, et al.
Publicado: (2014)

Agar gel immunodiffusion analysis using baculovirus-expressed recombinant bovine leukemia virus envelope glycoprotein (gp51/gp30(T)-)
por: Lim, Seong In, et al.
Publicado: (2009)

JAK2 Inhibitor, Fedratinib, Inhibits P-gp Activity and Co-Treatment Induces Cytotoxicity in Antimitotic Drug-Treated P-gp Overexpressing Resistant KBV20C Cancer Cells
por: Oh, Yunmoon, et al.
Publicado: (2022)

Intracellular accumulation of Praziquantel in T lymphoblastoid cell lines, CEM (parental) and CEMvbl(P-gp-overexpressing)
por: Kigen, Gabriel, et al.
Publicado: (2016)

High Expression of Methylotrophic Yeast-Derived Recombinant Human Erythropoietin in a pH-Controlled Batch System
por: Maleki, Ahmad, et al.
Publicado: (2010)

P1482: RECOMBINANT ERYTHROPOIETIN IN AUTOIMMUNE HEMOLYTIC ANEMIA WITH INADEQUATE RETICULOCYTOSIS: A SINGLE CENTER PROSPECTIVE STUDY
por: Luca Pedone, Giacinto, et al.
Publicado: (2023)

Gliflozins, Erythropoietin, and Erythrocytosis: Is It Renal Normoxia- or Hypoxia-Driven?
por: Heyman, Samuel N., et al.
Publicado: (2023)

Professor G.P. Puppi, Leader of NP Division
por: CERN PhotoLab
Publicado: (1962)

Development of Classification Models for Identifying “True” P-glycoprotein (P-gp) Inhibitors Through Inhibition, ATPase Activation and Monolayer Efflux Assays
por: Rapposelli, Simona, et al.
Publicado: (2012)

Transport Inhibition of Digoxin Using Several Common P-gp Expressing Cell Lines Is Not Necessarily Reporting Only on Inhibitor Binding to P-gp
por: Lumen, Annie Albin, et al.
Publicado: (2013)

Expression and cellular trafficking of GP82 and GP90 glycoproteins during Trypanosoma cruzi metacyclogenesis
por: Bayer-Santos, Ethel, et al.
Publicado: (2013)

Erythrocytes and Erythropoietin
por: Föller, Michael, et al.
Publicado: (2011)

Glycan shield of the ebolavirus envelope glycoprotein GP
por: Peng, Weiwei, et al.
Publicado: (2022)

Preoperative recombinant human erythropoietin in anemic surgical patients
por: Monk, Terri G
Publicado: (2004)

Recombinant human erythropoietin therapy in critically ill patients
por: Georgopoulos, D, et al.
Publicado: (2005)

Acquired Pure Red Cell Aplasia and Recombinant Erythropoietin
por: Padhi, Somanath, et al.
Publicado: (2021)

Modified recombinant human erythropoietin with potentially reduced immunogenicity
por: Susantad, Thanutsorn, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9n3i3kj824s9v03hqdb9ll3q9l