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Could GILZ Be the Answer to Glucocorticoid Toxicity in Lupus?

Glucocorticoids (GC) are used globally to treat autoimmune and inflammatory disorders. Their anti-inflammatory actions are mainly mediated via binding to the glucocorticoid receptor (GR), creating a GC/GR complex, which acts in both the cytoplasm and nucleus to regulate the transcription of a host o...

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Detalles Bibliográficos
Autores principales: Flynn, Jacqueline K., Dankers, Wendy, Morand, Eric F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652235/
https://www.ncbi.nlm.nih.gov/pubmed/31379872
http://dx.doi.org/10.3389/fimmu.2019.01684