Cargando…
Could GILZ Be the Answer to Glucocorticoid Toxicity in Lupus?
Glucocorticoids (GC) are used globally to treat autoimmune and inflammatory disorders. Their anti-inflammatory actions are mainly mediated via binding to the glucocorticoid receptor (GR), creating a GC/GR complex, which acts in both the cytoplasm and nucleus to regulate the transcription of a host o...
Autores principales: | Flynn, Jacqueline K., Dankers, Wendy, Morand, Eric F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652235/ https://www.ncbi.nlm.nih.gov/pubmed/31379872 http://dx.doi.org/10.3389/fimmu.2019.01684 |
Ejemplares similares
-
Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ)
por: Dankers, Wendy, et al.
Publicado: (2022) -
GILZ Regulates the Expression of Pro-Inflammatory Cytokines and Protects Against End-Organ Damage in a Model of Lupus
por: Nataraja, Champa, et al.
Publicado: (2021) -
Glucocorticoids and Glucocorticoid-Induced-Leucine-Zipper (GILZ) in Psoriasis
por: Sevilla, Lisa M., et al.
Publicado: (2019) -
Implicating the Role of GILZ in Glucocorticoid Modulation of T-Cell Activation
por: Cannarile, Lorenza, et al.
Publicado: (2019) -
Development of novel treatment strategies for inflammatory diseases—similarities and divergence between glucocorticoids and GILZ
por: Cheng, Qiang, et al.
Publicado: (2014)