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Bryostatin‐1 ameliorated experimental colitis in Il‐10 (−/−) Mice by protecting the intestinal barrier and limiting immune dysfunction

Bryostatin‐1 (Bry‐1) has been proven to be effective and safe in clinical trials of a variety of immune‐related diseases. However, little is known about its effect on Crohn's disease (CD). We aimed to investigate the impact of Bry‐1 on CD‐like colitis and determine the mechanism underlying this...

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Detalles Bibliográficos
Autores principales: Zuo, Lugen, Li, Jing, Ge, Sitang, Ge, Yuanyuan, Shen, Mengdi, Wang, Yan, Zhou, Changmin, Wu, Rong, Hu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652299/
https://www.ncbi.nlm.nih.gov/pubmed/31251471
http://dx.doi.org/10.1111/jcmm.14457