Cargando…

Potentiation of ABCA3 lipid transport function by ivacaftor and genistein

ABCA3 is a phospholipid transporter implicated in pulmonary surfactant homoeostasis and localized at the limiting membrane of lamellar bodies, the storage compartment for surfactant in alveolar type II cells. Mutations in ABCA3 display a common genetic cause for diseases caused by surfactant deficie...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinting, Susanna, Li, Yang, Forstner, Maria, Delhommel, Florent, Sattler, Michael, Griese, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652914/
https://www.ncbi.nlm.nih.gov/pubmed/31210424
http://dx.doi.org/10.1111/jcmm.14397