Ethyl pyruvate attenuates ventilation‐induced diaphragm dysfunction through high‐mobility group box‐1 in a murine endotoxaemia model

Mechanical ventilation (MV) can save the lives of patients with sepsis. However, MV in both animal and human studies has resulted in ventilator‐induced diaphragm dysfunction (VIDD). Sepsis may promote skeletal muscle atrophy in critically ill patients. Elevated high‐mobility group box‐1 (HMGB1) leve...

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Detalles Bibliográficos
Autores principales: Liu, Yung‐Yang, Chen, Ning‐Hung, Chang, Chih‐Hao, Lin, Shih‐Wei, Kao, Kuo‐Chin, Hu, Han‐Chung, Chang, Gwo‐Jyh, Li, Li‐Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652995/
https://www.ncbi.nlm.nih.gov/pubmed/31339670
http://dx.doi.org/10.1111/jcmm.14478

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