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Spontaneous colitis in IL‐10‐deficient mice was ameliorated via inhibiting glutaminase1

Immunity imbalance and barrier damage in the intestinal mucosa are the main pathogenic factors of Crohn's disease (CD). Bis‐2‐(5‐phenylacetamido‐1,2,4‐thiadiazol‐2‐yl) ethyl sulfide (BPTES) is a glutaminase 1 (Gls1) inhibitor with the dual functions of increasing glutamine levels and immune reg...

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Detalles Bibliográficos
Autores principales:	Li, Jing, Zuo, Lugen, Tian, Yun, He, Yifan, Zhang, Zhichao, Guo, Pu, Ge, Yuanyuan, Hu, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653008/ https://www.ncbi.nlm.nih.gov/pubmed/31211512 http://dx.doi.org/10.1111/jcmm.14471

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