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Save your gut save your age: The role of the microbiome in stem cell ageing
The tremendous importance of microbiota in microbial homoeostasis, alterations in metabolism and both innate and adaptive immune systems has been well established. A growing body of evidence support that dysbiosis or compositional changes in gut microbiota is linked to the ageing of stem cells in te...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653314/ https://www.ncbi.nlm.nih.gov/pubmed/31207055 http://dx.doi.org/10.1111/jcmm.14373 |
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author | Tan, Yi Wei, Zongke Chen, Jiaoliu An, Junli Li, Manling Zhou, Liuyun Men, Yanhua Zhao, Shan |
author_facet | Tan, Yi Wei, Zongke Chen, Jiaoliu An, Junli Li, Manling Zhou, Liuyun Men, Yanhua Zhao, Shan |
author_sort | Tan, Yi |
collection | PubMed |
description | The tremendous importance of microbiota in microbial homoeostasis, alterations in metabolism and both innate and adaptive immune systems has been well established. A growing body of evidence support that dysbiosis or compositional changes in gut microbiota is linked to the ageing of stem cells in terms of dysregulations of metabolism, aberrant activation of the immune system as well as promoting epigenetic instability of stem cell. In this concise review, we elucidate recent emerging topics on microbiotic alterations and underlying mechanisms in stem cell ageing. |
format | Online Article Text |
id | pubmed-6653314 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-66533142019-08-01 Save your gut save your age: The role of the microbiome in stem cell ageing Tan, Yi Wei, Zongke Chen, Jiaoliu An, Junli Li, Manling Zhou, Liuyun Men, Yanhua Zhao, Shan J Cell Mol Med Reviews The tremendous importance of microbiota in microbial homoeostasis, alterations in metabolism and both innate and adaptive immune systems has been well established. A growing body of evidence support that dysbiosis or compositional changes in gut microbiota is linked to the ageing of stem cells in terms of dysregulations of metabolism, aberrant activation of the immune system as well as promoting epigenetic instability of stem cell. In this concise review, we elucidate recent emerging topics on microbiotic alterations and underlying mechanisms in stem cell ageing. John Wiley and Sons Inc. 2019-06-17 2019-08 /pmc/articles/PMC6653314/ /pubmed/31207055 http://dx.doi.org/10.1111/jcmm.14373 Text en © 2019 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Tan, Yi Wei, Zongke Chen, Jiaoliu An, Junli Li, Manling Zhou, Liuyun Men, Yanhua Zhao, Shan Save your gut save your age: The role of the microbiome in stem cell ageing |
title | Save your gut save your age: The role of the microbiome in stem cell ageing |
title_full | Save your gut save your age: The role of the microbiome in stem cell ageing |
title_fullStr | Save your gut save your age: The role of the microbiome in stem cell ageing |
title_full_unstemmed | Save your gut save your age: The role of the microbiome in stem cell ageing |
title_short | Save your gut save your age: The role of the microbiome in stem cell ageing |
title_sort | save your gut save your age: the role of the microbiome in stem cell ageing |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653314/ https://www.ncbi.nlm.nih.gov/pubmed/31207055 http://dx.doi.org/10.1111/jcmm.14373 |
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