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A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm
In asthma, airway smooth muscle (ASM) contraction and the subsequent decrease in airflow involve a poorly understood set of mechanical and biochemical events. Organ-level and molecular-scale models of the airway are frequently based on purely mechanical or biochemical considerations and do not accou...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653686/ https://www.ncbi.nlm.nih.gov/pubmed/31150010 http://dx.doi.org/10.1038/s41551-019-0366-7 |