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High IDO1 Expression Is Associated with Poor Outcome in Patients with Anal Cancer Treated with Definitive Chemoradiotherapy

BACKGROUND. This study characterizes the tumor‐immune microenvironment in pretreatment, localized anal squamous cell carcinoma (ASCC), including two markers that have not previously been studied in ASCC: indoleamine 2,3 dioxygenase 1 (IDO1) and human leukocyte antigen (HLA) class I. MATERIALS AND ME...

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Detalles Bibliográficos
Autores principales:	Mitra, Devarati, Horick, Nora K., Brackett, Diane G., Mouw, Kent W., Hornick, Jason L., Ferrone, Soldano, Hong, Theodore S., Mamon, Harvey, Clark, Jeffrey W., Parikh, Aparna R., Allen, Jill N., Ryan, David P., Ting, David T., Deshpande, Vikram, Wo, Jennifer Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Gastrointestinal Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656510/ https://www.ncbi.nlm.nih.gov/pubmed/30755500 http://dx.doi.org/10.1634/theoncologist.2018-0794

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