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Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
Vision impairment is one of the devastating complications of central nervous system tuberculosis (CNS TB). Optic atrophy is a sequelae of various forms of CNS TB which, ultimately, is responsible for vision impairment. It is usually the secondary optic atrophy which occurs in CNS TB. In this case re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656685/ https://www.ncbi.nlm.nih.gov/pubmed/31367519 http://dx.doi.org/10.1016/j.idcr.2019.e00579 |
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author | Narayanan, Santhosh Prakash, Divya Subramaniam, Gomathy |
author_facet | Narayanan, Santhosh Prakash, Divya Subramaniam, Gomathy |
author_sort | Narayanan, Santhosh |
collection | PubMed |
description | Vision impairment is one of the devastating complications of central nervous system tuberculosis (CNS TB). Optic atrophy is a sequelae of various forms of CNS TB which, ultimately, is responsible for vision impairment. It is usually the secondary optic atrophy which occurs in CNS TB. In this case report, we present the story of an immunocompetent woman presenting as bilateral visual loss. She was found to have primary optic atrophy. Neuroimaging revealed features of chronic meningitis. Polymerase chain reaction test for Mycobacterium tuberculosis was positive in cerebrospinal fluid. Although secondary optic atrophy is common in the CNS TB, as a complication of meningitis, primary optic atrophy per se is infrequently reported. |
format | Online Article Text |
id | pubmed-6656685 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-66566852019-07-31 Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient Narayanan, Santhosh Prakash, Divya Subramaniam, Gomathy IDCases Article Vision impairment is one of the devastating complications of central nervous system tuberculosis (CNS TB). Optic atrophy is a sequelae of various forms of CNS TB which, ultimately, is responsible for vision impairment. It is usually the secondary optic atrophy which occurs in CNS TB. In this case report, we present the story of an immunocompetent woman presenting as bilateral visual loss. She was found to have primary optic atrophy. Neuroimaging revealed features of chronic meningitis. Polymerase chain reaction test for Mycobacterium tuberculosis was positive in cerebrospinal fluid. Although secondary optic atrophy is common in the CNS TB, as a complication of meningitis, primary optic atrophy per se is infrequently reported. Elsevier 2019-07-11 /pmc/articles/PMC6656685/ /pubmed/31367519 http://dx.doi.org/10.1016/j.idcr.2019.e00579 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Narayanan, Santhosh Prakash, Divya Subramaniam, Gomathy Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient |
title | Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient |
title_full | Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient |
title_fullStr | Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient |
title_full_unstemmed | Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient |
title_short | Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient |
title_sort | bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656685/ https://www.ncbi.nlm.nih.gov/pubmed/31367519 http://dx.doi.org/10.1016/j.idcr.2019.e00579 |
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