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Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient

Vision impairment is one of the devastating complications of central nervous system tuberculosis (CNS TB). Optic atrophy is a sequelae of various forms of CNS TB which, ultimately, is responsible for vision impairment. It is usually the secondary optic atrophy which occurs in CNS TB. In this case re...

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Detalles Bibliográficos
Autores principales: Narayanan, Santhosh, Prakash, Divya, Subramaniam, Gomathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656685/
https://www.ncbi.nlm.nih.gov/pubmed/31367519
http://dx.doi.org/10.1016/j.idcr.2019.e00579
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author Narayanan, Santhosh
Prakash, Divya
Subramaniam, Gomathy
author_facet Narayanan, Santhosh
Prakash, Divya
Subramaniam, Gomathy
author_sort Narayanan, Santhosh
collection PubMed
description Vision impairment is one of the devastating complications of central nervous system tuberculosis (CNS TB). Optic atrophy is a sequelae of various forms of CNS TB which, ultimately, is responsible for vision impairment. It is usually the secondary optic atrophy which occurs in CNS TB. In this case report, we present the story of an immunocompetent woman presenting as bilateral visual loss. She was found to have primary optic atrophy. Neuroimaging revealed features of chronic meningitis. Polymerase chain reaction test for Mycobacterium tuberculosis was positive in cerebrospinal fluid. Although secondary optic atrophy is common in the CNS TB, as a complication of meningitis, primary optic atrophy per se is infrequently reported.
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spelling pubmed-66566852019-07-31 Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient Narayanan, Santhosh Prakash, Divya Subramaniam, Gomathy IDCases Article Vision impairment is one of the devastating complications of central nervous system tuberculosis (CNS TB). Optic atrophy is a sequelae of various forms of CNS TB which, ultimately, is responsible for vision impairment. It is usually the secondary optic atrophy which occurs in CNS TB. In this case report, we present the story of an immunocompetent woman presenting as bilateral visual loss. She was found to have primary optic atrophy. Neuroimaging revealed features of chronic meningitis. Polymerase chain reaction test for Mycobacterium tuberculosis was positive in cerebrospinal fluid. Although secondary optic atrophy is common in the CNS TB, as a complication of meningitis, primary optic atrophy per se is infrequently reported. Elsevier 2019-07-11 /pmc/articles/PMC6656685/ /pubmed/31367519 http://dx.doi.org/10.1016/j.idcr.2019.e00579 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Narayanan, Santhosh
Prakash, Divya
Subramaniam, Gomathy
Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
title Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
title_full Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
title_fullStr Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
title_full_unstemmed Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
title_short Bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
title_sort bilateral primary optic neuropathy as the presenting manifestation of tuberculosis in an immunocompetent patient
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656685/
https://www.ncbi.nlm.nih.gov/pubmed/31367519
http://dx.doi.org/10.1016/j.idcr.2019.e00579
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