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Diffusion kurtosis MRI as a predictive biomarker of response to neoadjuvant chemotherapy in high grade serous ovarian cancer

This study assessed the feasibility of using diffusion kurtosis imaging (DKI) as a measure of tissue heterogeneity and proliferation to predict the response of high grade serous ovarian cancer (HGSOC) to neoadjuvant chemotherapy (NACT). Seventeen patients with HGSOC were imaged at 3 T and had biopsy...

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Detalles Bibliográficos
Autores principales: Deen, Surrin S., Priest, Andrew N., McLean, Mary A., Gill, Andrew B., Brodie, Cara, Crawford, Robin, Latimer, John, Baldwin, Peter, Earl, Helena M., Parkinson, Christine, Smith, Sarah, Hodgkin, Charlotte, Patterson, Ilse, Addley, Helen, Freeman, Susan, Moyle, Penny, Jimenez-Linan, Mercedes, Graves, Martin J., Sala, Evis, Brenton, James D., Gallagher, Ferdia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656714/
https://www.ncbi.nlm.nih.gov/pubmed/31341212
http://dx.doi.org/10.1038/s41598-019-47195-4