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In vitro and in vivo effects of insulin-producing cells generated by xeno-antigen free 3D culture with RCP piece

To establish widespread cell therapy for type 1 diabetes mellitus, we aimed to develop an effective protocol for generating insulin-producing cells (IPCs) from adipose-derived stem cells (ADSCs). We established a 3D culture using a human recombinant peptide (RCP) petaloid μ-piece with xeno-antigen f...

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Detalles Bibliográficos
Autores principales: Ikemoto, Tetsuya, Feng, Rui, Iwahashi, Shu-ichi, Yamada, Shinichiro, Saito, Yu, Morine, Yuji, Imura, Satoru, Matsuhisa, Munehide, Shimada, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656749/
https://www.ncbi.nlm.nih.gov/pubmed/31341242
http://dx.doi.org/10.1038/s41598-019-47257-7