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In vitro and in vivo effects of insulin-producing cells generated by xeno-antigen free 3D culture with RCP piece
To establish widespread cell therapy for type 1 diabetes mellitus, we aimed to develop an effective protocol for generating insulin-producing cells (IPCs) from adipose-derived stem cells (ADSCs). We established a 3D culture using a human recombinant peptide (RCP) petaloid μ-piece with xeno-antigen f...
Autores principales: | Ikemoto, Tetsuya, Feng, Rui, Iwahashi, Shu-ichi, Yamada, Shinichiro, Saito, Yu, Morine, Yuji, Imura, Satoru, Matsuhisa, Munehide, Shimada, Mitsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656749/ https://www.ncbi.nlm.nih.gov/pubmed/31341242 http://dx.doi.org/10.1038/s41598-019-47257-7 |
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