XBP-1 Remodels Lipid Metabolism to Extend Longevity

The endoplasmic reticulum unfolded protein response (UPR(ER)) is a cellular stress response that maintains homeostasis within the secretory pathway, regulates glucose and lipid metabolism, and influences longevity. To ask whether this role in lifespan determination depends upon metabolic intermediar...

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Detalles Bibliográficos
Autores principales: Imanikia, Soudabeh, Sheng, Ming, Castro, Cecilia, Griffin, Julian L., Taylor, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656787/
https://www.ncbi.nlm.nih.gov/pubmed/31315038
http://dx.doi.org/10.1016/j.celrep.2019.06.057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656787/
https://www.ncbi.nlm.nih.gov/pubmed/31315038
http://dx.doi.org/10.1016/j.celrep.2019.06.057

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