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XBP-1 Remodels Lipid Metabolism to Extend Longevity
The endoplasmic reticulum unfolded protein response (UPR(ER)) is a cellular stress response that maintains homeostasis within the secretory pathway, regulates glucose and lipid metabolism, and influences longevity. To ask whether this role in lifespan determination depends upon metabolic intermediar...
Autores principales: | Imanikia, Soudabeh, Sheng, Ming, Castro, Cecilia, Griffin, Julian L., Taylor, Rebecca C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656787/ https://www.ncbi.nlm.nih.gov/pubmed/31315038 http://dx.doi.org/10.1016/j.celrep.2019.06.057 |
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