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Genetic diversity of cytochrome P450 1A2 with different metabolic activities in domestic cats

Knowledge of genetic polymorphisms of metabolizing enzymes of medical drugs and xenobiotics including cytochrome P450 (CYP) is very limited in cats. We investigated polymorphisms in CYP1A2, one of the major CYP isoforms in the feline liver. Wild-type and three non-synonymous polymorphic variants, bu...

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Detalles Bibliográficos
Autores principales:	SUGIYAMA, Souta, UNO, Yasuhiro, AMANO, Tomoko, KITAZAWA, Takio, TERAOKA, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2019
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656809/ https://www.ncbi.nlm.nih.gov/pubmed/31118351 http://dx.doi.org/10.1292/jvms.19-0106

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