Cardioprotective Effects of Sphingosine-1-Phosphate Receptor Immunomodulator FTY720 in a Clinically Relevant Model of Cardioplegic Arrest and Cardiopulmonary Bypass

Objective: FTY720, an immunomodulator derived from sphingosine-1-phosphate, has recently demonstrated its immunomodulatory, anti-inflammatory, anti-oxidant, anti-apoptotic and anti-inflammatory properties. Furthermore, FTY720 might be a key pharmacological target for preconditioning. In this preclin...

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Detalles Bibliográficos
Autores principales: Ahmed, Naseer, Mehmood, Adeela, Linardi, Daniele, Sadiq, Soban, Tessari, Maddalena, Meo, Sultan Ayoub, Rehman, Rehana, Hajjar, Waseem M., Muhammad, Nazeer, Iqbal, Muhammad Perwaiz, Gilani, Anwar-ul-Hassan, Faggian, Giuseppe, Rungatscher, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656862/
https://www.ncbi.nlm.nih.gov/pubmed/31379576
http://dx.doi.org/10.3389/fphar.2019.00802

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