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Modeling the Amplification of Immunoglobulins through Machine Learning on Sequence-Specific Features
Successful primer design for polymerase chain reaction (PCR) hinges on the ability to identify primers that efficiently amplify template sequences. Here, we generated a novel Taq PCR data set that reports the amplification status for pairs of primers and templates from a reference set of 47 immunogl...
Autores principales: | Döring, Matthias, Kreer, Christoph, Lehnen, Nathalie, Klein, Florian, Pfeifer, Nico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656877/ https://www.ncbi.nlm.nih.gov/pubmed/31341211 http://dx.doi.org/10.1038/s41598-019-47173-w |
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