Keratoconus progression associated with hormone replacement therapy

PURPOSE: To report a postmenopausal patient with keratoconus who experienced significant progression after using hormone replacement therapy. OBSERVATIONS: A 51-year-old woman with previously stable keratoconus presented with acute disease progression following hormone replacement therapy in the con...

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Detalles Bibliográficos
Autores principales: Coco, Giulia, Kheirkhah, Ahmad, Foulsham, William, Dana, Reza, Ciolino, Joseph B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656926/
https://www.ncbi.nlm.nih.gov/pubmed/31372581
http://dx.doi.org/10.1016/j.ajoc.2019.100519
Descripción
Sumario:PURPOSE: To report a postmenopausal patient with keratoconus who experienced significant progression after using hormone replacement therapy. OBSERVATIONS: A 51-year-old woman with previously stable keratoconus presented with acute disease progression following hormone replacement therapy in the context of prophylactic hysterectomy and bilateral ovariosalpingectomy. Over a 14-month period after starting hormone therapy, the steepest K increased from 63.7D to 71.5D in the right eye and from 65.8D to 78.1D in the left eye. CONCLUSIONS: Hormone replacement therapy may amplify progression of keratoconus.

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