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Could Postnatal Age–Related Uridine Diphosphate Glucuronic Acid Be a Rate‐Limiting Factor in the Metabolism of Morphine During the First Week of Life?

Neonates experience dramatic changes in the disposition of drugs after birth as a result of enzyme maturation and environmental adjustment, challenging therapeutic decision making. In this research, we establish postnatal age, postmenstrual age, and body weight as physiologically reasonable predicto...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Lewis, Tamorah R., Moore, Jason N., Kraft, Walter K., Gauda, Estelle B., Sartori, David, Moody, David E., Gobburu, Jogarao V. S., Ivaturi, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656938/
https://www.ncbi.nlm.nih.gov/pubmed/31044547
http://dx.doi.org/10.1002/psp4.12407