Evaluating the Role of Janus Kinase Pathways in Platelet Homeostasis Using a Systems Modeling Approach

Maintaining platelet homeostasis is important to avoid spontaneous bleeding and organ damage. Thrombopoietin, the primary regulator of platelet production, is affected by and acts in part via Janus kinase (JAK)‐signal transducer and activator of transcription (STAT)–mediated mechanisms. Interleukin‐...

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Detalles Bibliográficos
Autores principales: Koride, Sarita, Nayak, Satyaprakash, Banfield, Christopher, Peterson, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656939/
https://www.ncbi.nlm.nih.gov/pubmed/31044523
http://dx.doi.org/10.1002/psp4.12419

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