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Systematic analysis of the intersection of disease mutations with protein modifications

BACKGROUND: Perturbed posttranslational modification (PTM) landscapes commonly cause pathological phenotypes. The Cancer Genome Atlas (TCGA) project profiles thousands of tumors allowing the identification of spontaneous cancer-driving mutations, while Uniprot and dbSNP manage genetic disease-associ...

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Detalles Bibliográficos
Autores principales:	Simpson, Claire M., Zhang, Bin, Hornbeck, Peter V., Gnad, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657027/ https://www.ncbi.nlm.nih.gov/pubmed/31345222 http://dx.doi.org/10.1186/s12920-019-0543-2

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