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High baseline Tie1 level predicts poor survival in metastatic breast cancer

BACKGROUND: Angiopoietin growth factors (Angs) regulate angiogenesis and lymphangiogenesis by binding to the endothelial Tie2 receptor. Ang2 expression is elevated in tissue hypoxia and inflammation, which also induce cleavage of the extracellular domain of the orphan Tie1 receptor. Here we have exa...

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Detalles Bibliográficos
Autores principales:	Tiainen, Leena, Korhonen, Emilia A., Leppänen, Veli-Matti, Luukkaala, Tiina, Hämäläinen, Mari, Tanner, Minna, Lahdenperä, Outi, Vihinen, Pia, Jukkola, Arja, Karihtala, Peeter, Aho, Sonja, Moilanen, Eeva, Alitalo, Kari, Kellokumpu-Lehtinen, Pirkko-Liisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657075/ https://www.ncbi.nlm.nih.gov/pubmed/31340773 http://dx.doi.org/10.1186/s12885-019-5959-8

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