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In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study
BACKGROUND: Magnetic resonance imaging (MRI)-guided pulsed focused ultrasound combined with the infusion of microbubbles (pFUS+MB) induces transient blood-brain barrier opening (BBBO) in targeted regions. pFUS+MB, through the facilitation of neurotherapeutics’ delivery, has been advocated as an adju...
Autores principales: | Sinharay, Sanhita, Tu, Tsang-Wei, Kovacs, Zsofia I., Schreiber-Stainthorp, William, Sundby, Maggie, Zhang, Xiang, Papadakis, Georgios Z., Reid, William C., Frank, Joseph A., Hammoud, Dima A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657093/ https://www.ncbi.nlm.nih.gov/pubmed/31345243 http://dx.doi.org/10.1186/s12974-019-1543-z |
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