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Interfering cellular lactate homeostasis overcomes Taxol resistance of breast cancer cells through the microRNA-124-mediated lactate transporter (MCT1) inhibition

BACKGROUND: Breast cancer, the most common invasive cancer of women, is a malignant neoplasm and the second main cause of cancer death. Resistance to paclitaxel (Taxol), one of the frequently used chemotherapy agents for breast cancer, presents a major clinical challenge. Recent studies revealed tha...

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Detalles Bibliográficos
Autores principales:	Hou, Lu, Zhao, Yi, Song, Guo-qing, Ma, Ying-han, Jin, Xiao-hu, Jin, Si-li, Fang, Yi-han, Chen, Yi-chong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657142/ https://www.ncbi.nlm.nih.gov/pubmed/31367191 http://dx.doi.org/10.1186/s12935-019-0904-0

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